Recent advancements are showcasing intelligent, autonomous AI systems designed to integrate models and tools for acting on behalf of users. Pioneering work from Google demonstrates these capabilities across diverse applications. The Gemini model, for example, functions as an expert astronomy assistant, accurately classifying cosmic events while providing explanations and assessing its own uncertainty. Google Earth AI, leveraging Gemini-powered agents, offers planetary-scale geospatial understanding for disaster preparedness and environmental analysis. In healthcare, initiatives include DeepSomatic for precision cancer medicine and an AI-powered personal health coach on Fitbit, utilizing agentic architectures with conversational, data science, and domain expert agents for personalized guidance. Accessibility is also enhanced by StreetReaderAI, making Street View navigable for blind and low-vision users through multimodal AI and interactive chat. Beyond Google's contributions, XR Blocks has introduced an open-source framework for rapidly prototyping AI-driven Extended Reality experiences. Complementing these developments, Amazon's Marc Brooker has outlined the essential infrastructure components for effective AI operations, with AWS's new AgentCore framework designed to empower developers in this space. These innovations collectively highlight the transformative impact of these systems in accelerating discovery and augmenting human capabilities.